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Reduced expression of glutathione s-transferase alpha 4 promotes vascular neointimal hyperplasia in ckd
Interchangeability and the Automatic Substitution Question A biosimilar can be approved as biosimilar without being designated interchangeable. Interchangeability requires additional evidence that the biosimilar can be substituted for the reference biologic without increased risk compared to using the reference product alone, and without involvement of the prescribing physician [41]
For example, once-weekly exenatide (PLGA microspheres) commonly caused small injection-site nodules or bumps
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